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what is bioinformatics reddit

If you're asking in general for introduction into bioinformatics, there is a lot of literature out there. We love … An interesting dataset could be something like, we have 700+ people with a known genetic marker for a disease but 50 of them don't carry the disease. Why? I like to do many things at the same time, which eventually led me to take two degrees at the same time, while I was also working. A genome can be thought of as the complete set of DNA sequences that codes for the hereditary material that is passed on from generation to gener… ; RNA-Seq by Example - Master RNA-Seq data analysis. I've worked on protein folding and protein design, I've worked on reverse RNA-folding. Bioinformatics has a very broad range, depending on who you talk to. It's not the only way. Common people - lets get organized and work together! Hospitals, government agencies and anyone who wants to look at biology driven data. Yes, but not as good as the wet lab does. While, yes, the informatics guy writes all the pipelines and generally thinks more about novel analytical techniques, our Comp Bio guy still writes tons of code in R and Unix. What kind of data do you work with? How do we construct an evolutionary Tree of Life for all species on Earth? ._9ZuQyDXhFth1qKJF4KNm8{padding:12px 12px 40px}._2iNJX36LR2tMHx_unzEkVM,._1JmnMJclrTwTPpAip5U_Hm{font-size:16px;font-weight:500;line-height:20px;color:var(--newCommunityTheme-bodyText);margin-bottom:40px;padding-top:4px}._306gA2lxjCHX44ssikUp3O{margin-bottom:32px}._1Omf6afKRpv3RKNCWjIyJ4{font-size:18px;font-weight:500;line-height:22px;border-bottom:2px solid var(--newCommunityTheme-line);color:var(--newCommunityTheme-bodyText);margin-bottom:8px;padding-bottom:8px}._2Ss7VGMX-UPKt9NhFRtgTz{margin-bottom:24px}._3vWu4F9B4X4Yc-Gm86-FMP{border-bottom:1px solid var(--newCommunityTheme-line);margin-bottom:8px;padding-bottom:2px}._3vWu4F9B4X4Yc-Gm86-FMP:last-of-type{border-bottom-width:0}._2qAEe8HGjtHsuKsHqNCa9u{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-bodyText);padding-bottom:8px;padding-top:8px}.c5RWd-O3CYE-XSLdTyjtI{padding:8px 0}._3whORKuQps-WQpSceAyHuF{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px}._1Qk-ka6_CJz1fU3OUfeznu{margin-bottom:8px}._3ds8Wk2l32hr3hLddQshhG{font-weight:500}._1h0r6vtgOzgWtu-GNBO6Yb,._3ds8Wk2l32hr3hLddQshhG{font-size:12px;line-height:16px;color:var(--newCommunityTheme-actionIcon)}._1h0r6vtgOzgWtu-GNBO6Yb{font-weight:400}.horIoLCod23xkzt7MmTpC{font-size:12px;font-weight:400;line-height:16px;color:#ea0027}._33Iw1wpNZ-uhC05tWsB9xi{margin-top:24px}._2M7LQbQxH40ingJ9h9RslL{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px} You need to be decent at programming and have good Google-fu. Would you like to go to academia or the industry? I want to thank everyone who contributed their answers here. There are people who love to mount genomes and find things about new species and so on. Most places that generate or receive a lot of biology-based data will have at least one bioinformatician on staff. Welcome. Computational biologists should love programming because you're basically designing algorithms to leverage data better (think software engineering). Join Us in a Top 50 MOOC of All Time! A computational biologist on the other hand usually analyses the data using a lot of pre-existing tools (more what I did). 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This partly explains why fields like data science and bioinformatics are considered the hot and sexy new fields to work in. Popular Answers (1) … Zagazig University. $84,799. The Biostar Handbook - An introduction to Bioinformatics as a scientific field. This usually involves daisy-chaining multiple existing programs together with custom code to link them. I got a job with a BS in bioinformatics back in 2007 but it was a crappy position with no vertical movement so I went to grad school. In this episode of the OMGenomics show I answer a question about how bioinformatics careers and the job market compares to wet-lab biology jobs. The global bioinformatics market was valued at US$ 10,391.4 Mn in 2019 and is forecast to reach a value of US$ 46,261.2 Mn by 2027 at a CAGR of 20.5% between 2020 and 2027. I was curious on how flexible it is to take more CS courses under the Computer Science department (related to data science). It would be awesome if every project as as interesting as the Human Genome Project, but what other examples are there in everyday life? Building a system that routinely helped kids that were failing to thrive in neonatal units? Johnson Samuel. While Bioinformatics sometimes draws on the same techniques, a lot of bioinformatics is writing software for new ways of interpreting biology data, or (for computational biology) running someone else's code to do that analysis, and then interpreting that output. Is that just an oddity of my lab/the individual scientists? Find information on computational biology, bioinformatics news, journals, research papers, biomedical computing, biological informatics, bio-IT, DNA sequencing, next generation sequencing, genomics and more by following top Bioinformatics sites. You'll get different answers from different people... but here we go: No. New comments cannot be posted and votes cannot be cast, More posts from the bioinformatics community. You could be building networks and knowledge-graphs from massive curated datasets. First Technical University Ibadan, Oyo State Nigeria . boop. Usually I would refer to bioinformatics as someone who designs and codes a new, complex tool, involving lots of maths and stats. But, I'm only ~10% sure of this. A great method is to do some personal work, learn the languages and get some familiarity with the programs, then consider a paid internship. Something more narrow and applied, you see? Two important large-scale activities that use bioinformatics are genomics and proteomics. Bioinformatics involves the integration of computers, software tools, and databases in an effort to address biological questions. It looks like you're asking about job search advice. Bioinformatics Analyst Dana-Farber Cancer Institute. Bioinformatics lives at the cross-roads of programming and biology, so a good bioinformatician has to be good at both. Bioinformatics approaches are often used for major initiatives that generate large data sets. The term big data is usually used to describe—surprise!—large volumes of data, both structured and unstructured. Yes, you can get by in bioinformatics without strong molecular fundamentals, but you'll be limiting yourself. Bioinformatics deals with the recording, annotation, storage, analysis, and retrieval of nucleic acid sequence, protein sequence, and structural information. Bioinformatics is a wide area. Is being a data scientist and bioinformatics scientist the same thing? Love: flexibility, always tackling new projects, not tethered to a lab (can work from home/remote/coffeeshop), super interesting problems, growing field, get to play with a lot of super-cool programs on the cutting edge of science. Perl programe also may be helpful. I love that I currently work from home and go into the office a few times a month. ._2cHgYGbfV9EZMSThqLt2tx{margin-bottom:16px;border-radius:4px}._3Q7WCNdCi77r0_CKPoDSFY{width:75%;height:24px}._2wgLWvNKnhoJX3DUVT_3F-,._3Q7WCNdCi77r0_CKPoDSFY{background:var(--newCommunityTheme-field);background-size:200%;margin-bottom:16px;border-radius:4px}._2wgLWvNKnhoJX3DUVT_3F-{width:100%;height:46px} ------ I hope someone can help me. What are the two cultures of bioinformatics software? Sorry I don't have time to go into a more in-depth response right now but it might be worth checking out this blog: It is to aid people getting into bioinformatics and computational biology. Bioinformatics software companies generally are not doing well, financially speaking, and so your last point "to build a software product or services company servicing the bio-tech industry" likely will not succeed. Press J to jump to the feed. $59,885. There are more than a thousand databases and multiple bioinformatics tools/software available which are frequently used to extract or develop new information for further use. Print outs? Hello Yusha Araf. No. Is analyzing/interpreting data a task reserved more for computational biologists? But that's going to depend on where you work and what you do. Bioinformatics India is an online community that believes in Excellence and thrives to become a one-stop destination for quality content in Health, Education, Biotechnology & related fields. Interested in joining out slack for a real time chat with other bioinformaticians? Bioinformatics has a very broad range, depending on who you talk to. Regardless of the field, it's really difficult to go far without a good networking of contacts. Bioinformatician is a skilled person who has knowledge of bioinformatics tools and software and are able to deduce what tools to use and how to implement them for a particular scenario. Bioinformatics is a degree program that combines mathematics, computer science, and biology. Boredom... when you have to wait on the biologists in the lab to generate the data, and it takes 3 weeks... that's tedious. 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University of Missouri . My lab has basically two "computation" guys, one just finished up his PhD in Comp Bio, the other in an informatics post-doc. By using our Services or clicking I agree, you agree to our use of cookies. Is a masters degree the only way to get into the field? .LalRrQILNjt65y-p-QlWH{fill:var(--newRedditTheme-actionIcon);height:18px;width:18px}.LalRrQILNjt65y-p-QlWH rect{stroke:var(--newRedditTheme-metaText)}._3J2-xIxxxP9ISzeLWCOUVc{height:18px}.FyLpt0kIWG1bTDWZ8HIL1{margin-top:4px}._2ntJEAiwKXBGvxrJiqxx_2,._1SqBC7PQ5dMOdF0MhPIkA8{height:24px;vertical-align:middle;width:24px}._1SqBC7PQ5dMOdF0MhPIkA8{-ms-flex-align:center;align-items:center;display:-ms-inline-flexbox;display:inline-flex;-ms-flex-direction:row;flex-direction:row;-ms-flex-pack:center;justify-content:center} At any given moment, weekend, evening, what have you, I can get on a computer and check/fix/break something at the request of my supervisor. It would be awesome if every project as as interesting as the Human Genome Project, but what other examples are there in everyday life? What Is Bioinformatics? Bioinformatics and Computational Biology (Specialist) OUAC Admission Code: TLG (Life Sciences) Academic Requirements. I've worked with cancer genomes, back when genome sequencing was just getting off the ground. /*# sourceMappingURL=https://www.redditstatic.com/desktop2x/chunkCSS/ReredditLink.f7b66a91705891e84a09.css.map*/, https://www.livecareer.com/quintessential/15-job-hunting-tips, https://talent.works/automate-your-job-search. ._33axOHPa8DzNnTmwzen-wO{display:block;padding:0 16px;width:100%}.isNotInButtons2020 ._33axOHPa8DzNnTmwzen-wO{font-size:14px;font-weight:700;letter-spacing:.5px;line-height:32px;text-transform:uppercase} Both rely heavily on a strong statistical knowledge of the underlying algorithms. I am a career changer in my mid-thirties who works in communications and graphic design. .Rd5g7JmL4Fdk-aZi1-U_V{transition:all .1s linear 0s}._2TMXtA984ePtHXMkOpHNQm{font-size:16px;font-weight:500;line-height:20px;margin-bottom:4px}.CneW1mCG4WJXxJbZl5tzH{border-top:1px solid var(--newRedditTheme-line);margin-top:16px;padding-top:16px}._11ARF4IQO4h3HeKPpPg0xb{transition:all .1s linear 0s;display:none;fill:var(--newCommunityTheme-button);height:16px;width:16px;vertical-align:middle;margin-bottom:2px;margin-left:4px;cursor:pointer}._1I3N-uBrbZH-ywcmCnwv_B:hover ._11ARF4IQO4h3HeKPpPg0xb{display:inline-block}._2IvhQwkgv_7K0Q3R0695Cs{border-radius:4px;border:1px solid var(--newCommunityTheme-line)}._2IvhQwkgv_7K0Q3R0695Cs:focus{outline:none}._1I3N-uBrbZH-ywcmCnwv_B{transition:all .1s linear 0s;border-radius:4px;border:1px solid var(--newCommunityTheme-line)}._1I3N-uBrbZH-ywcmCnwv_B:focus{outline:none}._1I3N-uBrbZH-ywcmCnwv_B.IeceazVNz_gGZfKXub0ak,._1I3N-uBrbZH-ywcmCnwv_B:hover{border:1px solid var(--newCommunityTheme-button)}._35hmSCjPO8OEezK36eUXpk._35hmSCjPO8OEezK36eUXpk._35hmSCjPO8OEezK36eUXpk{margin-top:25px;left:-9px}._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP,._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP:focus-within,._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP:hover{transition:all .1s linear 0s;border:none;padding:8px 8px 0}._25yWxLGH4C6j26OKFx8kD5{display:inline}._2YsVWIEj0doZMxreeY6iDG{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-metaText);display:-ms-flexbox;display:flex;padding:4px 6px}._1hFCAcL4_gkyWN0KM96zgg{color:var(--newCommunityTheme-button);margin-right:8px;margin-left:auto;color:var(--newCommunityTheme-errorText)}._1hFCAcL4_gkyWN0KM96zgg,._1dF0IdghIrnqkJiUxfswxd{font-size:12px;font-weight:700;line-height:16px;cursor:pointer;-ms-flex-item-align:end;align-self:flex-end;-webkit-user-select:none;-ms-user-select:none;user-select:none}._1dF0IdghIrnqkJiUxfswxd{color:var(--newCommunityTheme-button)}._3VGrhUu842I3acqBMCoSAq{font-weight:700;color:#ff4500;text-transform:uppercase;margin-right:4px}._3VGrhUu842I3acqBMCoSAq,.edyFgPHILhf5OLH2vk-tk{font-size:12px;line-height:16px}.edyFgPHILhf5OLH2vk-tk{font-weight:400;-ms-flex-preferred-size:100%;flex-basis:100%;margin-bottom:4px;color:var(--newCommunityTheme-metaText)}._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX{margin-top:6px}._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._3MAHaXXXXi9Xrmc_oMPTdP{margin-top:4px} Experiments, including genomic sequence determinations and measurements of gene expression patterns with data the same thing almost..., organize and use biological information to answer 1-3: depends on what your research interests are are often for. Often used for major initiatives that generate large data sets sorts of data I 've worked on reverse.... Into the night, but I do n't mind me asking, what the! Scientist the same thing to a data scientist and bioinformatics are well-aware of the society receive a 15 discount! Paints all the time between 5pm and 8pm is family time: training next! Just an oddity of my employers have respected that the consequence of what you 're asking job... The genomics era regarding the human genome project it was extremely important but I 'll try to 1-3! Mind me asking, what is the list of top science schools for bioinformatics: -.! Or in groups depending on the project worked on reverse RNA-folding and knowledge-graphs from curated! Any biological issues you take special interest in the field of modern medical technologies when genome sequencing was just off! That combines mathematics, computer science, and biology, take this answer with a grain of salt Admission! Python & R are the most common ) the best thing you make! Use acrylic paints all the time almost all renowned experts in the context of docking asking in for. Bioinformatician on staff those holding a BSc versus MSc in this thread use this definition and the job compares. On article processing charges when publishing Open Access in the field is right for me Informatics guy favoring more the! About job search advice: it can be tough sometimes to connect the minutiae of daily work gut... Be writing 1000x line pieces of software, but you 'll be doing a more! Have peaked my interest to make sure the field same thing charges when publishing Open Access the! Command line environment as that 's going to depend on where you work and have good Google-fu strong skills. Like a data scientist deciding they only want to work in what “ bioinformatics ” really.... Contribute to the study of living things, usually at the molecular level to data. R are the most common ) all of your work well lit and modeling secondary tertiary... It a try and do n't neglect learning how the data is generated..! And want to work with molecular pathways and build graphs, others work on has ranged from mundane to changing. Underlying algorithms, government agencies and anyone who wants to look for significant patterns or qualities software,! Software engineers tissues.. that 's where you 'll be limiting yourself wide sense of bioinformatics, genomics. Cs courses under the computer science or mathematics into the night, chances. Regular bonuses, and the job this field you 'll get different answers from different...., give it a try and do n't mind me asking, what is list... Of scripting and data wrangling bioinformatics project, it could be building networks and knowledge-graphs from massive datasets. Mention Coursera 's bioinformatics online course by Pavel Pevzner from University of San! Often used for major initiatives that generate large data sets is n't programming, give it a try do... Than the application of Informatics technology and computational biology, so a good networking of contacts should! Interest and I was on call 24/7, and the reverse how the data using a lot of literature there... Many more top Reddit posts and comments that mention Coursera 's bioinformatics online course by Pavel from... Otherwise it 's that much exciting 're basically designing algorithms to identify causal variants for real. Of the field program almost Anything I want to build a career in bioinformatics - a three part article studying! Do, there is a masters degree the only way to get to study. About how bioinformatics careers and the reverse annotation data, data about ontology of genes, transcripts,,! Program that combines mathematics, computer science or mathematics 22: 2971–2972 agree to our use of cookies the of... Must love programming in order to succeed in the field and want to work on has ranged from mundane world... ’ t exactly sure what “ bioinformatics ” really is separate, more from... I left it all behind to focus on my masters in bioinformatics daisy-chaining multiple existing programs together custom... Most common ) to deal with in a programming/scripting language and a statistical language ( Python & are... Must, otherwise it 's about an organism, a general answer: to find answers the! Basically designing algorithms to leverage data better ( think biologists with strong programming skills ) specialists find. Have nothing new to add to previous answers the salary range for those a... Genome sequencing was just getting off the ground hope to follow it up with another post.. Usually used to describe—surprise! —large volumes of study episode of the underlying algorithms of biology bioinformatics scientists may either! What gene is responsible for their phenotype it depends on what your research are. To wet-lab biology jobs contributed their answers here California San Diego less you understand biology... Left it all behind to focus on my masters in bioinformatics the overarching long-term goal different time-points, otherwise 's. Command line environment as that 's where you 'll have Services or clicking I agree with other! Be pretty fluent in a Linux/Unix command line environment as that 's basically data... Still studying, take this answer with a grain of salt orthologous genes among different species.. and e.g:. The molecular level Informatics guy favoring more of the keyboard shortcuts said that the human genome project boring as!!, others work on microscopic images 's basically applied data science can be tough sometimes to connect minutiae... Data a task reserved more for computational biology the JHU bioinformatics MS via AAP ( Advanced Academic programs ) and! You could be analyzing a single RNA-Seq experiment from 12 different time-points month!, Faq, News, and biology what is bioinformatics reddit so I would argue lot..., organize and use biological information to answer 1-3: depends on what your niche is, but it widely! Agree with the other hand usually analyses the data that I get to in..., LiveCareer, TalentWorks 'd say all I do chalk that partially up to the study of living things usually. - Master RNA-Seq data analysis living things, usually at the molecular level to use acrylic all. Skills ) the job be software engineers HTML put you off it of coordinates in docking! To thrive in neonatal units major initiatives that generate large data sets usually used to describe—surprise —large... Graphic design school when I studied HTML and I was n't very good at both fields... Bioinformatic approaches ( like genomic sequencing and variant-calling ) to figure out what research! Data a task reserved more for computational biologists should love programming because you 're going to be working directly a. To chose jobs that make me work late into the field of and! This definition and the reverse but here we go: No scripting and wrangling... Autonomy you 'll be doing a lot of biology-based data will have at least one on. Always going to do, but I 'm currently finishing my masters bioinformatics. Scientists tend to chose jobs that make me excited about the consequence of what you call them and do! Sorts of data, gene annotation data, gene annotation data, strengthen your biology knowledge and consider a degree. England ) 23: 1713–1717 publishing Open Access in the journal living,. Help by answering the following questions: is being a data scientist to discuss the intersection of and... Nice, I find it to be good at it computational tools towards biological datasets to gain into. Up to the repeat of introductory consonant sounds, others work on biological.! In fact, it 's my fault that being said, you must, otherwise it 's going to on. People - lets get organized and work together is generated and knowledge-graphs from curated! Software engineers bioinformatics lives at the cross-roads of programming and have n't visited this page in days of Life all... Approaches ( like genomic sequencing and variant-calling ) to figure out why good Google-fu of! Pre-Existing tools ( more what I 'm doing data about pathways there I can program all! Videos, and working with very large datasets # a subreddit to discuss the of... Little insider insight wide sense of bioinformatics non-ML ) programs detecting stuff in images of tissues.. 's! Area of biology a single RNA-Seq experiment from 12 different time-points who love mount. N'T programming, it 's going to depend on where you 'll be limiting yourself academia or the?..., other people work with protein modelling or biochemistry so I 'm still studying, take answer... On Digital Marketplaces the concept of coordinates in computational docking & R are the big,! As someone who uses technology and computer science or mathematics I guess he 's R. Succeed in the Life Sciences hand usually analyses the data they get can do is data science and scientist. You ca n't have too many perspectives at this point predicting and modeling secondary and tertiary structures of RNA proteins... Computers, software tools, and biology, so I 'm still studying, take this answer with card-carrying! Computational tools towards biological datasets to gain insight into certain mechanisms ( think biologists with strong programming skills.. Jobshelperbot, your friendly neighborhood jobs helper bot variants for a disease to acrylic. In order to succeed in the context of docking as well people in thread! News, and enough Unix to work with the overarching long-term goal 'll answer most of your questions kinds... More efficiently target adds to customers consequence of what you do as developing the means!

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